What is Elastin F?
Sourced from bonito fish caught in Shizuoka and Kagoshima prefectures in Japan, Elastin F is a low-molecular-weight elastin peptide that helps support “young” and elastic blood vessels. Extracted from bulbus arteriosus of the fish, which is a small chamber connecting gill and heart, Elastin F is particularly high in elastin. Hence, elastin F extracted from it can be clearly distinguished from other types of fish elastin, which are commonly extracted from fish skin that is high in collagen. Based on EVG staining, bulbus arteriosus is rich in elastic fibers that are stained dark violet. In the fish skin, elastic fiber is rarely seen and mostly are collagen fiber that are stained red. Thus, bulbus arteriosus of the fish is a suitable raw material for elastin.
Elastin derived from bovine ligaments has long been used for nutraceuticals and cosmetics. However, the increased concerns for bovine spongiform encephalopathy (BSE), commonly known as mad cow disease, has urged researchers to look for a safe, alternate source of elastin. Elastin F derived from fish is a highly safe alternative. This superior, low-molecular-weight elastin peptide contain two speciﬁc amino acids – Desmosine and Isodesmosine that are crucial to the elasticity of cross-linking elastin ﬁbres. These two amino acids do not occur in proteins other than elastin. The concentrations of Desmosine and Isodesmosine and their crosslinks decrease with age. Together with degradation of elastin fibres, this would lead to the stiffening of arterial wall and reduced elasticity in other body tissues. Dietary intake of Elastin F sends “signals” to the body to trigger elastin synthesis, which in turn:
- Improve elasticity of blood vessels
- Stimulate skin fibroblast to synthesize collagen and elastin
- Improve skin firmness and texture
- Reduce platelet aggregation
- Reduce knee pain